|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Receptors, Tumor Necrosis Factor, Type I
|
|
Descriptor Spanish:
|
|
Receptores Tipo I de Factores de Necrosis Tumoral
|
|
Descriptor Portuguese:
|
|
Receptores Tipo I de Fatores de Necrose Tumoral
|
|
Synonyms English:
|
|
Antigens, CD120a
CD120a Antigens
Receptors, Tumor Necrosis Factor, Member 1A
Tumor Necrosis Factor Receptor Superfamily, Member 1A
Tumor Necrosis Factor Receptor Type I
|
|
Tree Number:
|
|
D12.776.543.750.073.750
D12.776.543.750.705.852.760.597
D23.050.301.264.035.908
D23.101.100.110.912
|
|
Definition English:
|
|
A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. |
|
History Note English:
|
|
2005(1994)
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
38769
|
|
Unique Identifier:
|
|
D047888
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS SciELO LILACS LIS
|